Research chemicals only · Not for human use · DYOR

Peply Labs
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#11 popular
Emerging human
Metabolic

AOD-9604

aka hGH fragment 176-191

hGH fragment marketed for fat loss without GH side-effects

MW (Da)

1,817.13

Half-life

~30 min

Sequence

YLRIVQCRSVEGSCGF (modified)

Storage

Lyophilized 2–8 °C. Reconstituted refrigerate.

Research chemicals only. Not for human use. For research and educational purposes only. Always do your own due diligence and consult qualified professionals.

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Safety at a glance

Full safety details

Most-reported side effects

  • Mild injection-site reaction
  • Rarely headache

Don't use if…

  • Pregnancy

What it is

Modified C-terminal fragment of human growth hormone designed to retain GH's lipolytic action without raising IGF-1 or affecting blood sugar.

Mechanism of action

Activates beta-3 adrenergic receptor signaling in adipocytes, stimulating lipolysis and reducing lipogenesis. Does not bind GH receptor classically.

Reported benefits

  • Targeted fat loss—particularly stubborn / visceral fat
  • No IGF-1 elevation; no growth-related side effects
  • Often added to GLP-1 or GH stacks for adipose-specific support

Evidence notes

Met-X obesity trial (Phase IIb): modest fat loss but did not hit primary endpoint. Safe profile across human studies.